Table 1 Key ELSI
Basic research | Clinical research | Clinical context |
|---|---|---|
• Quality and integrity of research • Transparency and publication of results • Inherent tension between clinical progress, scientific caution and compliance with regulatory requirements | • Safety and efficacy of intervention (evidence-based) • Informed consent • Prohibitively high development costs • Time- and labour-intensive • Justice and affordability • Pressure to commercialize | • Unproven therapies • Right to try • Accuracy in advertising • Legitimacy of the informed consent obtained • Vulnerable population exposed to unjustifiable risks |