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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways

Fig. 2

a Representative flow cytometry results and hiPSC-EC differentiation efficiency when 10 μM of the p38MAPK inhibitor losmapimod (Losma) was supplemented in differentiation stage 1, 2, or 3. b. Representative flow cytometry results and hiPSC-EC differentiation efficiency when 5 μM of the ERK1/2 inhibitor SCH was supplemented in differentiation stage 1, 2, or 3. c Representative flow cytometry results and mean hiPSC-EC differentiation efficiency when both Losma and SCH were supplemented in differentiation stage 1, 2, or 3. Assessments of CD31 levels were compared with isotype controls. (***p < 0.001 vs any other treatment)

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