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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways

Fig. 5

hiPSC-ECs were differentiated from A PCBC16, B GRiPSC, C DP1-C9, D DP3-C6, and E PG-608 lines and evaluated for the expression of (1) CD31 and (2) CD144, for (3) Dil-ace-LDL uptake, for (4) tube formation on Matrigel, and for (5) EC lumen formation in fibrin-thrombin scaffolds. (Bar = 100 μm. Magnification of tubule formation and EC lumen = × 4). F Quantifications of numbers of nodes, junctions, and meshes formed by ECs on Matrigel. (n = 5 each for PCBC16, GRiPSC, DP1-C9, and DP3-C6; n = 4 for PG-608). (*p < 0.05 and **p < 0.01 vs PG-608. ^p < 0.01 vs DP1-C9. #p < 0.05 vs DP3-C6)

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Stem Cell Research & Therapy

ISSN: 1757-6512