Table 2 miRNAs expression profile of MSC-EVs from different studies

Baglio et al. 2015 [42]

Human adipose-derived MSCs, passages 2–3

miR-486-5p, miR-10a-5p, miR-10b-5p, miR-191-5p, and miR-222-3p

The five most abundant miRNAs accounted for 43–59% of the total miRNA reads.

Baglio et al. 2015 [42]

Human BM-derived MSCs, passages 2–3

miR-143-3p, miR-10b-5p, miR-486-5p, miR-22-3p, and miR-21-5p

Fang et al. 2016 [44]

Human umbilical cord-derived MSCs, passages 2–5

miR-21-5p, miR-125b-5p, miR-23a-3p, miR-100-5p, let-7f-5p, let-7a-5p, miR-145-5p, and miR-1260b

The top 8 miRNAs account for 40.7% of total miRNAs.

Ferguson et al. 2018 [45]

Human BM-derived MSCs, passages 1–7

miR-1246, miR-23a-3p, miR-451a, miR-125b-5p, miR-199a-3p, let-7a-5p, miR-4454, and miR-21-5p

The top 23 miRNAs account for 79.1% of total miRNAs.

Luther et al. 2018 [46]

B6 mouse BM-MSCs

miR-21a-5p, miR-486b-5p, miR-486a-3p, miR-143-3p, miR-92a-3p, miR-486a-5p, miR-486b-3p, and miR-22-3p