Stem Cell Research & Therapy

Table 1 Association between miR181b expression and clinicopathological factors in patients with NSCLC

From: miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC

Variable	No. of patients	miR181 expression		p (χ²)	NOTCH2 expression				p (χ²)	CD133 expression				p (χ²)	SOX2 expression				p (χ²)
Variable	No. of patients	High (n)	Low (n)	p (χ²)	(−) (n)	(+) (n)	(++) (n)	(+++) (n)	p (χ²)	(−) (n)	(+) (n)	(++) (n)	(+++) (n)	p (χ²)	(−) (n)	(+) (n)	(++) (n)	(+++) (n)	p (χ²)
All cases	116	57	59		24	33	27	32		3	43	61	9		8	14	40	54
Age (years)				0.196					0.356					0.828					0.324
≤ 55	35	14	21		8	6	10	11		1	15	17	2		2	5	8	20
> 55	81	43	38		16	27	17	21		2	28	44	7		6	9	32	34
Gender				0.578					0.595					0.239					0.782
Male	89	45	44		16	27	21	25		3	31	46	9		6	12	29	42
Female	27	12	15		8	6	6	7		0	12	15	0		2	2	11	12
Differentiation				0.684					0.002					0.015					0.044
Good/moderate	20	9	11		10	4	5	1		2	11	7	0		2	5	9	4
Poor	96	48	48		14	29	22	31		1	32	54	9		6	9	31	50
pT status				0.761					0.226					0.096					0.486
pT1	20	11	9		5	7	5	3		2	10	6	2		1	1	11	7
pT2	84	41	43		19	20	21	24		1	27	49	7		6	12	26	40
pT3–4	12	5	7		0	5	1	5		0	6	6	0		1	1	3	7
pN stage				0.005					0.186					0.109					0.004
pN0	85	49	35		18	29	18	20		1	31	44	9		2	11	30	42
pN1	14	3	11		1	3	4	6		0	5	9	0		1	2	3	8
pN2	17	5	13		5	1	5	6		2	7	8	0		5	1	7	4
pTNM stage				0.022					0.186					0.055					0.131
I	65	34	31		13	23	15	14		1	23	32	9		2	8	25	30
II	26	7	19		6	8	4	8		0	9	17	0		1	4	6	15
III	25	16	9		5	2	8	10		2	11	12	0		5	2	9	9

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