Fig. 3

Anti-cancer efficiencies of naïve MSC isolated from adult bone marrow (BM), adipose tissue (AT) or fetal umbilical cord (UC). a Radar graph depicting differences in frequencies of UC- (red), BM- (black), or AT-derived (blue) MSC associated with tumor suppressive activity in vivo and/or in vitro. The tumor suppression frequency for each MSC type relative to the other two is represented by vertical distances from graph center. Each outer vertex represents the maximum frequency (100%), equal to the sum of the three relative frequencies of the respective MSC types. Suppression rates are shown for four consolidated groups (presented in ascending order of size clockwise starting from “in vivo”). Values for the highest suppression rate in each of the four groups are shown. b Radar graph depicting differences in frequencies of UC- (red), BM- (black), or AT-derived (blue) MSC with respect to pro-tumorigenic behavior in vivo and/or in vitro. The tumor promotion frequency for each MSC type relative to the other two is represented by vertical distances from graph center. Each outer vertex represents the maximum frequency (100%), equal to the sum of the three relative frequencies of the respective MSC types. Promotion rates are shown for four consolidated groups (presented in ascending order of size clockwise starting from “in vivo”). Highest observed values for each of the groups are shown. c Distribution of pro- vs. antitumorigenic effects for each of the three naïve MSC types in vitro and in vivo (N = 26/46/25 for AT-/BM-/UC-MSC, respectively). In the case of UC-MSC, all pro-tumorigenic effects were observed in vitro