Table 1 Comparison of hematological parameters between rats infused with T2D+saline and T2D+WJMSCs-apelin after 42 days
Item | Group | |||||
|---|---|---|---|---|---|---|
T2D+WJMSCs-apelin (B) | T2D+saline (D) | Sham (N) | P value (B&D) | P value (B&N) | P value (D&N) | |
High-density lipoprotein | 1.06 ± 0.11 | 0.97 ± 0.36 | 1.03 ± 0.09 | 0.43 | 0.46 | 0.64 |
Low-density lipoprotein | 0.38 ± 0.07 | 0.38 ± 0.27 | 0.41 ± 0.09 | 0.97 | 0.42 | 0.73 |
Serum total protein | 63.36 ± 2.73 | 76.59 ± 25.83 | 66.01 ± 4.20 | 0.09 | 0.09 | 0.22 |
Alanine aminotransferase | 53.50 ± 10.68 | 61.59 ± 50.27 | 59.66 ± 14.66 | 0.59 | 0.28 | 0.91 |
Total cholesterol | 2.02 ± 0.18 | 2.43 ± 1.07 | 1.77 ± 0.39 | 0.21 | 0.55 | 0.08 |
Triglyceride | 2.32 ± 1.25 | 5.31 ± 7.60 | 0.98 ± 0.56 | 0.09 | 0.005 | 0.09 |
Serum albumin | 29.11 ± 1.32 | 32.13 ± 5.73 | 33.95 ± 2.65 | 0.09 | < 0.0001 | 0.37 |
Urea nitrogen | 5.78 ± 0.68 | 10.63 ± 11.91 | 6.63 ± 0.70 | 0.17 | 0.01 | 0.30 |
Creatinine | 44.65 ± 3.59 | 66.84 ± 41.86 | 43.34 ± 2.65 | 0.08 | 0.35 | 0.09 |
Uric acid | 60.08 ± 44.16 | 49.17 ± 37.49 | 72.00 ± 34.36 | 0.52 | 0.50 | 0.16 |
TNF-α (pg/mL) | 14.3 ± 3.14 | 51.2 ± 9 | 8.22 ± 2.11 | 0.007 | 0.003 | 0.004 |
IL-6 (pg/mL) | 50.21 ± 3.7 | 147.6 ± 7.13 | 42.03 ± 4.6 | 0.0002 | 0.011 | < 0.0001 |
APN (μg/mL) | 9.36 ± 2.21 | 6.46 ± 5.10 | 11.68 ± 2.17 | 0.11 | 0.012 | 0.027 |