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Table 2 Comparison of immunological parameters between rats infused with T2D+saline and T2D+WJMSCs-apelin before and after 42 days

From: Overexpression of apelin in Wharton’ jelly mesenchymal stem cell reverses insulin resistance and promotes pancreatic β cell proliferation in type 2 diabetic rats

Parameter

T2D+saline

T2D+WJMSCs-apelin

Sham

Prior treatment

42 days after treatment

Prior treatment

42 days after treatment

IgG(g/L)

11.3 ± 0.8

10.6 ± 0.9

11.0 ± 0.7

10.9 ± 0.6

10.8 ± 0.4

IgM(g/L)

1.13 ± 0.08

1.14 ± 0.11

1.10 ± 0.12

1.15 ± 0.14

1.08 ± 0.07

CD3(%)

65.8 ± 3.1

64.6 ± 2.2

66.1 ± 3.4

67.2 ± 4.7

66.3 ± 3.9

CD4(%)

39.2 ± 1.3

38.1 ± 1.7

38.9 ± 1.1

38.2 ± 1.6

39.3 ± 1.5

CD8(%)

22.9 ± 0.9

23.4 ± 1.2

22.4 ± 0.8

22.1 ± 1.4

22.7 ± 0.7

  1. No significant differences were shown in comparison of baseline with values measured after 42 days of rats with WJ-MSC-apelin or saline infusion. T2D+saline, type 2 diabetic rat with saline infusion; T2D+WJMSCs-apelin, type 2 diabetic rat with Wharton’s jelly mesenchymal stem cell-apelin infusion