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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Induced pluripotent stem cell-derived endothelial progenitor cells attenuate ischemic acute kidney injury and cardiac dysfunction

Fig. 3

Systemic human iPS cell-derived iEPC therapy reduced azotemia and systemic inflammation after acute kidney injury (AKI). a–c Plasma levels of blood urea nitrogen (BUN) and creatinine and interleukin-1β (IL-1β) in mice subjected to sham surgery or renal I/R injury treated with vehicle (AKI-V) and systemic iEPC or iPS therapy (AKI-iEPC or AKI-iPS). N = 7–18 per group. d Representative image illustrating the measurement of plasma indoxyl sulfate by liquid chromatography. FU indicates fluorescence unit. e Bar chart denoting plasma levels of indoxyl sulfate in each group. N = 5 per group. Data are expressed as mean ± SEM. *P < 0.05 AKI-V vs. Sham, #P < 0.05 AKI-iEPC or AKI-iPS vs. AKI-V group

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Stem Cell Research & Therapy

ISSN: 1757-6512