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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Impaired function of tendon-derived stem cells in experimental diabetes mellitus rat tendons: implications for cellular mechanism of diabetic tendon disorder

Fig. 6

The results of chondrogenesis differentiation assay. 6A: The gross view of the pellets of both hTDSCs and dTDSCs. The histological staining showed more chondrocyte-like cells with H&E staining (6B, 6C) and much higher proteoglycan deposition with Safranin O staining (6D, 6E) in dTDSCs formed pellets after CIM induced for 28 days. Scale bar = 100 μm. 6F–6I, 6L: The expression of Col II and SOX9 were also increased in dTDSCs than the controls with IHC staining. Scale bar = 50 μm. 6M, 6N: The expression of chondrogenesis-related marker genes was measured by qRT-PCR assays at day 14 under both basal medium and CIM incubation. N = 3 of each group. *p < 0.05

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Stem Cell Research & Therapy

ISSN: 1757-6512