Fig. 6

Fibroblast accumulation and ECM deposition are ameliorated in MSCs-Fstl1-treated ischemic myocardium. a Representative images of vimentin staining within the infarct border zone on post-therapy 7 days. Scale bar = 50 μm. qRT-PCR analysis of Fsp-1 (b), α-SMA (c), Col1a1 (e), and Fn1 (f) in peri-infarct myocardium on post-therapy 7 days (n = 3–4). d Western blot analysis of vimentin and α-SMA in ischemic myocardium on post-therapy 7 days. *P < 0.05; **P < 0.01; ***P < 0.001. MI, myocardial infarction; Fsp-1, fibroblast-specific protein-1; α-SMA, α-smooth muscle actin; Col1a1, type I collagen; Fn1, fibronectin; ns, not significant