TY - JOUR AU - Jia, Yachao AU - Zhu, Yu AU - Qiu, Shuo AU - Xu, Jia AU - Chai, Yimin PY - 2019 DA - 2019/01/11 TI - Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis JO - Stem Cell Research & Therapy SP - 12 VL - 10 IS - 1 AB - Distraction osteogenesis (DO) is an effective but lengthy procedure to fully induce bone regeneration in large bone defects. Accumulating evidence supports the role of exosomes secreted by endothelial progenitor cells (EPC-Exos) in stimulating angiogenesis, which is closely coupled with osteogenesis. This study aimed to investigate whether EPC-Exos promote bone regeneration during DO in rats. SN - 1757-6512 UR - https://doi.org/10.1186/s13287-018-1115-7 DO - 10.1186/s13287-018-1115-7 ID - Jia2019 ER -