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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Predictors of responders to mononuclear stem cell-based therapeutic angiogenesis for no-option critical limb ischemia

Fig. 5

Typical preoperative computed tomographic angiography (CTA) and longitudinal foot photos of a responder (a, b, c) and a non-responder (d, e, f). The case on the left side was a 37-year-old male diagnosed with thromboangiitis obliterans, characterized by progressive limb gangrene (b), occlusion level at popliteal artery (a), transcutaneous oxygen pressure of 15 mmHg, Log transplanted CD34+ cells of 8.17, and baseline blood fibrinogen < 4 g/L. The nomogram-based score was 192, indicating a probability of 0.76 to be a responder. His toe gangrene was debrided during the transplantation, and the wound healed completely within 6 months (c). The case on the right side was a 73-year-old male diagnosed with atherosclerosis obliterans, characterized by left foot rest pain, occlusion level at proximal superficial femoral artery (f), transcutaneous oxygen pressure of 12 mmHg, Log transplanted CD34+ cells of 7.38, and baseline blood fibrinogen < 4 g/L. The nomogram-based score was 110, indicating a probability of 0.18 to be a responder. His rest pain was not relieved and the fourth and fifth toes had gangrene at 6 months (e). The white arrows indicate the arterial occlusion level

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