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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes

Fig. 6

Changes in DNA methylation and gene expression during myogenesis in women and men. a, b Overlap of number of a CpG sites with significantly different methylation (q < 0.05) and b unique genes with significantly different gene expression (q < 0.05) in myoblasts versus myotubes from women (N = 11) and men (N = 13). c mRNA expression of selected genes with expression difference in myoblasts versus myotubes from either women or men. In women, p = 0.58 and q = 0.69 for NDUFC1, p = 0.07 and q = 0.14 for NDUFB9. In men, p = 0.08 and q = 0.14 for MYOD1, p = 0.89 and q = 0.92 for LDHB. *q < 0.05. Data are presented as mean ± SD

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