From: Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes
Phenotype | Women (n = 13) | Men (n = 13) | p value |
---|---|---|---|
Age (years) | 53.5 ± 7.9 | 52.4 ± 5.3 | 0.69 |
BMI (kg/m2) | 30.1 ± 6.8 | 28.8 ± 5.1 | 0.59 |
Weight (kg) | 84.9 ± 24.3 | 96.9 ± 17.2 | 0.16 |
Waist-hip ratio (waist/hip) | 0.85 ± 0.1 | 0.96 ± 0.07 | 5.1 × 10− 03 |
Hip circumference (cm) | 111.9 ± 14.0 | 107.5 ± 8.4 | 0.34 |
Waist circumference (cm) | 96.5 ± 22.1 | 103.5 ± 13.4 | 0.34 |
Android fat mass (kg) | 3.2 ± 2.1 | 3.1 ± 1.6 | 0.94 |
Gynoid fat mass (kg) | 6.8 ± 2.3 | 4.1 ± 1.4 | 1.8 × 10− 03 |
Whole body fat mass (kg) | 35.3 ± 16.0 | 26.5 ± 10.8 | 0.12 |
Whole body fat-free mass (kg) | 45.8 ± 8.7 | 66.5 ± 7.5 | 1.0 × 10− 06 |
Glucose 0 h (mmol/l) | 4.7 ± 0.5 | 5.1 ± 0.5 | 0.06 |
Glucose 2 h (mmol/l) * | 5.5 ± 1.5 | 5.3 ± 1.3 | 0.75 |
Insulin 0 h (pmol/l) * | 48.8 ± 33.6 | 66.3 ± 36.1 | 0.22 |
Insulin 2 h (pmol/l) * | 311.7 ± 176.8 | 373.4 ± 326.1 | 0.56 |
HOMA-IR* | 1.5 ± 1.1 | 2.2 ± 1.3 | 0.17 |
HOMA-β* | 111.1 ± 60.8 | 132.2 ± 92.3 | 0.50 |
P-cholesterol (total mmol/l) | 5.2 ± 0.8 | 5.3 ± 1.0 | 0.90 |
P-cholesterol HDL (mmol/l) | 1.7 ± 0.6 | 1.4 ± 0.4 | 0.11 |
P-cholesterol LDL (mmol/l) | 3.0 ± 0.4 | 3.4 ± 0.9 | 0.17 |
Systolic blood pressure (mmHg) | 127.4 ± 12.7 | 144.5 ± 12.8 | 2.2 × 10− 03 |
Diastolic blood pressure (mmHg) | 86.5 ± 10.7 | 90.6 ± 8.1 | 0.28 |
Heart rate (beats/min) | 68.5 ± 8.8 | 57.3 ± 10.9 | 8.5 × 10− 03 |
VO2 max (l/min) | 2.1 ± 0.7 | 2.9 ± 0.8 | 0.01 |
VO2 max per kg (ml/min/kg) | 24.7 ± 8.7 | 30.5 ± 11.4 | 0.15 |