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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases

Fig. 4

Next-generation sequencing. a Heat map of the top 100 differentially expressed genes (50 upregulated genes and 50 downregulated genes) and p21 (CDKN1A) between hHFMSCsEGFP and hHFMSCsOCT4. Red, upregulation; blue, downregulation. b GO biological process analysis of the enrichment of differentially expressed genes between hHFMSCsEGFP and hHFMSCsOCT4. c KEGG analysis of the enrichment of differentially expressed genes between hHFMSCsEGFP and hHFMSCsOCT4 in specific pathways. GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes

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Stem Cell Research & Therapy

ISSN: 1757-6512