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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling

Fig. 1

Identification of exosomes and uptake of exosomes by BM-MSCs. a Western blot analyses of exosomal markers CD63, CD81, Tsg101, and negative protein calnexin in BM-MSC lysates and BM-MSC-derived exosomes. b Characterization of BM-MSC-derived exosomes by transmission electron microscopy. PBS was used as control. Exosomes were round or oval with a diameter of approximately 40–100 nm. Scale bar = 200 nm. c Uptake of CM-DiI (red)-labeled exosomes in CM-DiO (green)-labeled BM-MSCs were observed using a fluorescence microscope after 24 h. Abbreviations: PBS, phosphate-buffered saline; BM-MSCs, bone marrow mesenchymal stem cells

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Stem Cell Research & Therapy

ISSN: 1757-6512