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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice

Fig. 2

Effect of adipogenic differentiation on gene expressions. a Preliminary microarray analysis on ADSCs differentiated towards adipocyte (AD) or undifferentiated (ADSC). Selected gene expression levels are shown. b Real-time PCR analysis of the gene expression levels of AP2 and EF1A in ADSC and AD. GAPDH was used as an internal control. Insulin mRNA levels (c) and C-peptide secretion levels (d) in furin-cleavable human insulin stably expressed ADSC and AD cells driven by EF1 or AP2 promoter. Data derived from three independent experiments were presented as mean ± SD. *p < 0.05 and **p < 0.01 were considered significant

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Stem Cell Research & Therapy

ISSN: 1757-6512