Fig. 4

Tissue compatibility of cytodex 3 and cytopore 1. 0.2 ml empty microcarriers were subcutaneously injected into of the nude mice. Gross view of cross-sections of cytodex 3- (a) and cytopore 1 (b)-formed structures 2 weeks after injection. Scale bar, 1 mm. c, d H&E staining on frozen sections of cytodex 3- (a) and cytopore 1 (b)-formed structures. Green dashed lines show the border of the microcarrier-formed structures. Scale bar, 50 μm. e, f Compositional analysis of cytopore 1-formed structures. e The cellulose backbone of cytopore 1 was demonstrated by Congo red staining. f The endothelial cells were examined by CD31 immunohistochemistry. Scale bar, 50 μm