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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human amnion-derived mesenchymal stem cell (hAD-MSC) transplantation improves ovarian function in rats with premature ovarian insufficiency (POI) at least partly through a paracrine mechanism

Fig. 4

Changes in ovarian function and histology after hAD-MSC transplantation. a The percentage of rats with abnormal estrous cycles was observed at 1, 4, and 8 weeks after hAD-MSC transplantation. bd Serum levels of AMH (b), FSH (c), and E2 (d) were evaluated at 0, 2, 4, and 8 weeks after hAD-MSC transplantation. e, f Changes in the histology of ovaries were analyzed using HE staining (e × 40), and the number of follicles at different stages was counted and compared (f) in the three groups at 4 weeks after hAD-MSC transplantation. *P < 0.05 and **P < 0.01. Scale bars, 100 μm

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