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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Fibroblast growth factor-5 promotes spermatogonial stem cell proliferation via ERK and AKT activation

Fig. 3

Differentially expressed genes in RNA-Seq were confirmed by Q-PCR. A total of 20 genes, including 10 SCOS Sertoli cells downregulated (FGF5, DKK1, IGF2, PNP, SEMA3A, CDH1, SPRY2, CDK6, MET and WNK4) (a) and upregulated (b) ones (SPP1, TP53I11, ADRA2A, PLA2G2A, NTN1, OSCAR, PRRX2, WFDC1, NGFR and MT3), from 308 DEGs were selected to validate the results of RNA-Seq. Note: OA obstructive azoospermia, SCOS Sertoli cell-only syndrome, SC Sertoli cell. Asterisk indicated statistically significant differences (P < 0.05)

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Stem Cell Research & Therapy

ISSN: 1757-6512