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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Applications of mesenchymal stem cell technology in bovine species

Fig. 1

Isolation, characterization, and potential applications of bovine mesenchymal stem cells. Bovine mesenchymal stem cells have been isolated from the uterus, umbilical cord, bone marrow, adipose tissue, placenta, and fetal fluids. After isolation, the cells are expanded and characterized to prove their mesenchymal nature. The ability to self-renew is an important feature to be characterized in vitro and can be done by analysis of colony unit formation (CFU) and population doubling time (PDT). The cells need to show the ability to differentiate into osteogenic, chondrogenic, and adipogenic lineages. The bovine-isolated cells have already been shown to be positive for some mesenchymal and pluripotent markers and negative for hematopoietic markers. After characterization, the cells can be injected into the animal for therapeutic applications. Uses of bovine MSC for treatment of joint injuries, mastitis, and bone injuries; preservation of genetic resources; manipulation of productivity; and use in biotechnology applied in animal reproduction have all been suggested

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