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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways

Fig. 2

ASC-MVs induce HUVECs migration, proliferation, and angiogenesis. a Images of migrated HUVECs taken at 24 h after treatments of PBS, 5 μg/ml ASC-MVs, and 10 μg/ml ASC-MVs, respectively. Scar bar, 100 μm. b Qualification of migrated cells given different treatments (n = 3). c Enhanced tube formation in HUVECs treated with 20 μg/ml ASC-MVs compared with the controls at different time point. Scar bar, 50 μm. d Qualification of closed tubular structures shown in c (n = 3). e Increased HUVEC proliferation at day 2 after 20 μg/ml ASC-MV treatment compared with the controls as evidenced by CCK8 assay (n = 5). **p < 0.01, ***p < 0.001, ****p < 0.0001

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