Fig. 3

Modulation of HaCAT and fibroblast function by ASC-MV administration. a Images of migrated fibroblasts taken at 24 h after treatments of PBS, 5 μg/ml ASC-MVs, and 10 μg/ml ASC-MVs, respectively. Scar bar, 100 μm. b Qualification of data shown in a (n = 3). c Images of migrated HaCAT given the above treatment. Scar bar, 100 μm. d Qualification of data shown in c (n = 3). e Increased HaCAT proliferation at days 2 and 3 after 20 μg/ml ASC-MV treatment compared with the controls as evidenced by CCK8 assay (n = 5). f Increased fibroblast proliferation at days 4 and 6 after 20 μg/ml ASC-MV treatment (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001