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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Immunoregulatory potential of mesenchymal stem cells following activation by macrophage-derived soluble factors

Fig. 2

TNF-α and IL-10 prime MSC to regulate cytokine secretion from pro-inflammatory macrophages. a TNF-α and IL-10 levels in media of MΦGM cultured in isolation or co-cultured with MSC primed or not (−) with CMGM or CMM. CM were incubated or not (−Ab) with neutralizing antibody (Ab) against TNF-α or IL-10. b TNF-α and IL-10 levels in media of MΦGM cultured in isolation or co-cultured with MSC primed or not (−) with the indicated doses of TNF-α, IL-10 or combinations of both cytokines. *p < 0.05

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