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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B

Fig. 4

Analysis of the combination of LINC00707 and miR-370-3p. a Schematic diagram of miR-370-3p putative binding sites in wild type and mutant LINC00707. b Dual-luciferase reporter assay to detect the binding sites between LINC00707 and miR-370-3p. c Ago2-RIP to verify the binding of lncC00707 to miR-370-3p. d miR-370-3p level determined in HBMSCs at 0, 5, 10, 15, and 20 days after osteogenic induction by qRT-PCR. e Correlation analysis was performed between miR-370-3p and LINC00707 levels at indicated times after osteogenic induction. f miR-370-3p level following interference and overexpression of LINC00707 was determined by qRT-PCR. Data represent the mean ± S.D. *P<0.05, **P<0.01

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