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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Long noncoding RNA LINC00707 sponges miR-370-3p to promote osteogenesis of human bone marrow-derived mesenchymal stem cells through upregulating WNT2B

Fig. 7

Effect of WNT2B on osteogenic induction. a mRNA levels of WNT2B, RUNX2, OCN, and ALP in HBMSCs transfected with si-WNT2B at 3 and 7 days after osteogenic induction. b Protein levels of WNT2B, RUNX2, OCN, and ALP in HBMSCs transfected with si-WNT2B after oncogenic induction for 7 days. c Activity of ALP in HBMSCs transfected with si-WNT2B after osteogenic induction for 7 days. d ARS staining and ALP staining in HBMSCs transfected with si-WNT2B after osteogenic induction for 7 days. e HE and Masson Trichrome staining were performed in WNT2B silenced HBMSCs in vivo. Data represent the mean ± S.D. *P<0.05, **P<0.01

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