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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis

Fig. 5

Administration of primed Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) significantly changes cytokine levels in lymph node (LN) cells. Skin draining LN cells were stimulated with anti-CD3/CD28 antibodies for 2 days. Levels of a interleukin (IL)-17, b IL-10, c IL-13 and d interferon-gamma (IFN-γ) in the culture medium were measured by enzyme-linked immunosorbent assays (ELISAs). Data are presented as the mean ± SEM (N = 6 per group). **, p < 0.005; ***, p < 0.0005 compared with the control group; #, p < 0.05 compared with the AD group

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