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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects

Fig. 3

miRNA-21-seeded scaffolds repair calvarial bone defects in rats. a Micro-CT images of newly formed bone in the Lenti-miRNA-21/β-TCP/BMSC, Lenti-LacZ/β-TCP/BMSC, and β-TCP groups. b Quantitative analyses of the BMD and TbTh of the newly formed bone in the three groups (six animals in each group). The experiment was repeated three times. c Histomorphological observations of the newly formed bone in the three groups

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