Fig. 2

hUC-MSCs suppress systemic inflammation. a Count of circulating lymphocytes, neutrophils, and monocytes. b Ratio of CD4+/CD8+ T cells and proportion of circulating regulatory T cells (Treg; CD4+CD25+FOXP3+) and dendritic cells (DCs; CD1a+CD80+CD86+). c Serum levels of cytokines, chemokines, and growth factors. EGF, epidermal growth factor; eotaxin, eosinophil chemotactic factor; FGF, fibroblast growth factor; G-CSF, granulocyte colony-stimulating factor; HGF, hepatocyte growth factor; IL, interleukin; INF-γ, interferon γ; IP-10, interferon-inducible protein-10; I-TAC, interferon-inducible T cell α chemoattractant; MCP-1, monocyte chemoattractant protein-1; MDC, macrophage-derived chemokine; MIF, macrophage migration inhibitory factor; MIG, monokine induced by interferon γ; MIP-1α, macrophage inflammatory protein-1α; Rantes, regulated upon activation normal T cell expressed and secreted; TNF-α, tumor necrosis factor. N = 5–6; error bars, SEM. Mann–Whitney U test, *P < 0.05, ^&P < 0.01, and ^$P < 0.001