Fig. 6

BMSCs suppressed SM-induced inflammation by targeting the TLR4 signaling pathway. TRL4, NFκB p50 and NFκB p65 expression in lung tissue (a) and in the Raw264.7 cell model (b, c). d Comparison of TNF-α, IL-1β, IL-6, and IL-10 in the lung tissue of SM-exposed wild type and TLR4 knockout mice as determined by ELISA. *p < 0.05 compared with the WT group; **p < 0.01 compared with the WT group