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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

Fig. 5

The effect of IASM on viability, apoptosis, senescence, and proliferation of MSCs in rat joint. a, b, c, d The Calcein-AM (green)/PI (red) (a), Caspase-3 (brown) (b), SA-β-Gal (green) (c), and EdU (green) (d) staining of MSCs in gel scaffold in cartilage defect 1 week after transplantation. Nucleus were stained by Hoechst 33342 (blue). Bars = 50 μm. Positive cells were calculated respectively (right, n = 3). *P < 0.05, **P < 0.01

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