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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Intraarticular senescent chondrocytes impair the cartilage regeneration capacity of mesenchymal stem cells

Fig. 6

The effect of IASM on BMSCs cartilage regeneration. a Safranin O/fast green staining of cartilage repair 6 weeks after BMSCs implantation. The residual immature area (RIA, white dashed line) and residual gel area (RGA, yellow dashed line) were calculated (right, n = 3). Bars = 400 μm. bd The immunohistochemistry staining for Col II (b), Agg (c), and Col I (d) of cartilage repair 6 weeks after BMSCs implantation. Bars = 400 μm. e Safranin O/fast green staining of cartilage repair 3 months after BMSCs implantation. Bars = 400 μm. The Pineda score of cartilage regeneration was evaluated (right, n = 3). *P < 0.05, **P < 0.01

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