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Table 2 Subtypes of skin stem cells

From: Skin tissue regeneration for burn injury

Cell type (Refs)

Localization

Specific markers

Epidermal stem cells [63, 64, 85, 86]

Basal layer of the epidermis

b1high/melanoma chondroitin sulfate proteoglycan positive, α6high/CD71dim, p63

Melanocyte stem cells [87,88,89]

Follicle bulge region and hair germ

Dct, Pax3, Sox

Follicular stem cells [90,91,92,93]

Follicle bulge region

CD34, CD200, K15, K19, Lgr5, Lhx2, NFATC1, NFIB, PHLDA1, Sox9

Hematopoietic stem cells [94]

Follicle dermal papillae

CD34 for lymphoid and hematopoietic progenitor cells

Sebaceous gland stem cells [95]

Sebaceous glands and infundibulum

Blimp1

Mesenchymal stem-like cells[96]

Dermis

CD70+, CD90+, CD105+, CD34-

Neural progenitor cells [97]

Follicle dermal papillae

S100 for schwannomas, peripheral neural tissue astrocytes; HMB45, a neuraminidase-sensitive oligosaccharide side chain of a glycoconjugate

  1. Refs references