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Table 1 Survival of Fanca−/− DNA-PKcs3A/3A embryos and pups

From: The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance

DNA-PKcs+/3A Fanca+/− × DNA-PKcs+/3A Fanca+/− intercross
  DNA-PKcs3A/3A Fanca+/+ or DNA-PKcs3A/3A Fanca+/− DNA-PKcs+/+ Fanca−/− or DNA-PKcs+/3A Fanca−/− DNA-PKcs 3A/3A Fanca −/− Other genotypes
E10.5 embryos (96 screened) Expected 24 24 6 42
Observed 22 21 5 48
Live pups (170 screened) Expected 42 42 10 76
Observed 35 36 0 99