Table 1 Survival of Fanca−/− DNA-PKcs3A/3A embryos and pups
From: The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance
DNA-PKcs+/3A Fanca+/− × DNA-PKcs+/3A Fanca+/− intercross | |||||
|---|---|---|---|---|---|
|  | DNA-PKcs3A/3A Fanca+/+ or DNA-PKcs3A/3A Fanca+/− | DNA-PKcs+/+ Fanca−/− or DNA-PKcs+/3A Fanca−/− | DNA-PKcs 3A/3A Fanca −/− | Other genotypes | |
E10.5 embryos (96 screened) | Expected | 24 | 24 | 6 | 42 |
Observed | 22 | 21 | 5 | 48 | |
Live pups (170 screened) | Expected | 42 | 42 | 10 | 76 |
Observed | 35 | 36 | 0 | 99 | |