Table 2 Survival of Fancc−/− DNA-PKcs3A/3A embryos and pups
From: The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance
DNA-PKcs+/3A Fancc+/− × DNA-PKcs+/3A Fancc+/− intercross | |||||
|---|---|---|---|---|---|
|  | DNA-PKcs3A/3A Fancc+/+ or DNA-PKcs3A/3A Fancc+/− | DNA-PKcs+/+ Fancc−/− or DNA-PKcs+/3A Fancc−/− | DNA-PKcs 3A/3A Fancc −/− | Other genotypes | |
E10.5 embryos (56 screened) | Expected | 14 | 14 | 3 | 25 |
Observed | 12 | 13 | 2 | 29 | |
Live pups (106 screened) | Expected | 26 | 26 | 6 | 48 |
Observed | 19 | 22 | 0 | 65 | |