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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injury

Fig. 3

The effects of MDL28170 on the expression levels of pro-inflammatory and anti-inflammatory factors at 24 h after TBI. a–d Expression levels of pro-inflammatory factors IL-1β, IL-6, TNF-α, and inflammatory transcription factor NFκB decreased significantly after treatment with MDL28170 at 30 min after TBI compared with the vehicle group, respectively. e, f Increased expression levels of anti-inflammatory factors IL-10 and IL-4, respectively. *P < 0.05, **P < 0.01 by one-way ANOVA followed by Turkey post-tests (n = 4). TBI, traumatic brain injury

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