Skip to main content
Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

Fig. 7

Comparative analysis of the miRNA profiles of ADSCs versus AFSCs demonstrated a distinct profile with mutually present and exclusive miRNAs. a 2D PCA plot shows two distinct clusters along the PC1 axis that correspond to the ADSCs (red) and AFSCs (green). b Weighted Venn diagram. The graph consists of miRNAs expressed in ADSCs (red) and in AFSCs (green). 47 miRNAs were found to be exclusively present in the ADSC samples whereas 207 miRNA were exclusive for AFSCs. 519 miRNA were mutually found in both cell types. c Hierarchical clustering heat map of the top 50 regulated miRNAs in multiple comparisons. MicroRNAs are displayed in the rows and samples in the columns. The expression levels are indicated via the colour coding. The shades of blue and red refer to the absolute expression levels; the brighter the blue, the lower the expression level, and the brighter the red, the higher the expression level. The dendrograms are based on cosine column/row clustering

Back to article page