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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: MiR-378a suppresses tenogenic differentiation and tendon repair by targeting at TGF-β2

Fig. 2

Tendon injury healing was impaired in miR-378a Tg mice. a H&E and immunohistochemistry staining (Collagen type 1 and Thbs4) of tendon defect in WT and Tg mice at week 2. b Increased cell numbers in defect regions of Tg mice at week 2 (n = 6, *, p < 0.05 by Student’s t test). c, d Semi-quantification of Collagen type I and Thbs4 expression area in the defect region at week 2 (n = 6, *, p < 0.05 by Student’s t test). e H&E and immunohistochemistry staining (Collagen type 1 and Thbs4) of tendon defect in WT and Tg mice at week 4. f Increased cell numbers in defect regions of Tg mice at week 4 (n = 6, *, p < 0.05 by Student’s t test). g, h Semi-quantification of the Collagen type 1 and Thbs4 expression area in the defect region at week 4 (n = 6, *p < 0.05 by Student’s t test). Scale bar = 100 μm

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