Fig. 3

Survival and cardiac functional repair after cell transplantation in mice post-MI. Animals underwent MI + saline, MI + Nestin⁺ BMSC, or MI + Nestin⁻ BMSC surgeries (n = 12 for each group) and received follow-up echocardiography in 1 and 4 weeks post-MI. a Four-week survival. Data were analyzed using a Kaplan–Meier regression, and significance was determined using the log-rank test. b Representative M-mode tracings from mice receiving MI + saline, MI + Nestin⁺ BMSCs, or MI + Nestin⁻ BMSCs at 1 and 4 weeks post-MI. c Structural and functional parameters derived from echocardiography measurements. The means ± SEMs of the results are shown. *p < 0.05, **p < 0.01. MI, myocardial infarction. LVEF, left ventricular ejection factor. LVFS, left ventricular fractional shortening. LVEDV, left ventricular end-diastolic volume. LVESV, left ventricular end-systolic volume