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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Exosomes secreted by mesenchymal stromal/stem cell-derived adipocytes promote breast cancer cell growth via activation of Hippo signaling pathway

Fig. 3

Adipocyte exosomes promote breast cancer cell proliferation and migration. a MTS analysis of MCF7 cells treated with adipocyte exosomes or PBS. b Transwell migration assays showed that MCF7 cells treated with adipocyte exosomes have a higher migratory capacity. Left is a representative microscopic image of crystal violet staining. Right shows the statistical results. c Migratory ability of MCF7 co-cultured with adipocyte exosomes or PBS was determined by wound healing assay. Left is a representative microscopic image. Right shows the statistical results at 24 h. d MTS analysis of MCF7 cells treated with a culture medium or exosome-depleted culture medium. e Transwell migration assays showed that MCF7 cells treated with a culture medium have higher migratory capacity than an exosome-depleted culture medium. Left is a representative microscopic image of crystal violet staining. Right shows the statistical results. f Migratory ability of MCF7 in a culture medium or exosome-depleted culture medium was determined by wound healing assay. Left is a representative microscopic image. Right shows the statistical results at 24 h

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