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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: IGF-1 overexpression improves mesenchymal stem cell survival and promotes neurological recovery after spinal cord injury

Fig. 4

Modulation of inflammatory mediators after SCI and treatment. Transcripts for a iNOS, b Arg1, c Chi3I3, d Mrc1, e Nfe2I2, f Cat, and g Gpx3 were determined in SCI segment homogenates from saline (n = 5), BMMSC (n = 5), or BMMSC-IGF1-treated mice, by RT-qPCR. Values represent means ± SEM. Concentrations of h malondialdehyde (MDA), measured by MDA Oxidative Stress Assay, and i nitrite, determined by the Griess method, in SCI segment homogenates from naive, (n = 5), saline (n = 5), BMMSC (n = 5), or BMMSC-IGF1-treated mice. Values represent mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001

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