Skip to main content
Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: IGF-1C domain-modified hydrogel enhances therapeutic potential of mesenchymal stem cells for hindlimb ischemia

Fig. 4

CS-IGF-1C hydrogel augmented the proangiogenic effects of hP-MSCs. a BLI tracked the VEGFR2-Fluc expression following hP-MSCs transplanted in HLI models. Colored scale bar represents the bioluminescence average radiance in photons/s/cm2/steradian. b Quantitative analysis data revealed the improved proangiogenic effects of CS-IGF-1C hydrogel. Data are expressed as mean ± SEM. *P < 0.05 versus PBS; #P < 0.05 versus hP-MSCs; $P < 0.05 versus hP-MSCs + CS. c Representative images of muscle sections stained for CD31 (red) at day 14. Nuclei were counter stained with DAPI. d Quantitative analysis of CD31 immunostaining in each group. The number of capillary vessels was counted in five randomly selected areas. Scale bar, 100 μm. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01 versus sham; ##P < 0.01 versus PBS; $$P < 0.01 versus hP-MSCs; &&P < 0.01 versus hP-MSCs + CS hydrogel

Back to article page