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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: IGF-1C domain-modified hydrogel enhances therapeutic potential of mesenchymal stem cells for hindlimb ischemia

Fig. 7

Therapeutic mechanisms of CS-IGF-1C hydrogel for hindlimb ischemia. a Apoptotic-related gene expression. The expression levels of Bax, Caspase-3, and Bad were evaluated by RT-PCR in each group on day 14. b The expression level of TNF-α was evaluated by RT-PCR in each group on day 14. c Expression levels of VEGF and Ang-2 were evaluated by RT-PCR in each group on day 14. Data were expressed as mean ± SEM. *P < 0.05, **P < 0.01 versus sham; #P < 0.05, ##P < 0.01 versus PBS; $P < 0.05 versus hP-MSCs; &P < 0.05 versus hP-MSCs + CS

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