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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: microRNA-301b-3p downregulation underlies a novel inhibitory role of long non-coding RNA MBNL1-AS1 in non-small cell lung cancer

Fig. 1

LncRNA MBNL1-AS1 may affect NSCLC via TGFBR2 by sponging miR-301b-3p. a Heat map of the 50 DEGs retrieved from GSE101929. The abscissa indicated the sample number and the ordinate indicated the DEG. The upper right histogram indicated color gradation; each rectangle in the figure corresponded to the level of a gene in a sample. b Subcellular localization of lncRNA MBNL1-AS1 in LncATLAS. CN RCI refers to the ratio of lncRNA expression in cytoplasm and nucleus. FPKM refers to fragments per kilobase of exon model per million mapped fragments. c Comparisons of lncRNA MBNL1-AS1-targeted miRNAs in RAID database and differential miRNAs in GSE102286. d Expression of miR-301b, miR-30d, miR-218, and miR-30a in GSE102286 chip. Blue indicated the adjacent normal tissues and red indicated NSCLC tissues. e Comparisons of miR-301b-3p-targeted genes in mirDIP, miRDB, miRSearch, RNA22, and miRTarBase databases and DEGs from GSE33532 chips. f TGFBR2 expression in GSE33532 chips. DEGs, differentially expressed genes; MBNL1-AS1, muscleblind-like 1-antisense RNA 1; NSCLC, non-small cell lung cancer; TGFBR2, transforming growth factor beta receptor II

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