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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: microRNA-301b-3p downregulation underlies a novel inhibitory role of long non-coding RNA MBNL1-AS1 in non-small cell lung cancer

Fig. 2

LncRNA MBNL1-AS1 is poorly expressed in NSCLC tissues and cells. a lncRNA MBNL1-AS1 expression in NSCLC tissues and adjacent normal tissues determined using RT-qPCR (n = 56). b lncRNA MBNL1-AS1 expression in tissues with and without lymph node metastasis determined using RT-qPCR. c lncRNA MBNL1-AS1 expression in NSCLC cell lines (A549, H1299, and SK-MES-1) and human normal lung epithelial cell line BEAS-2B determined using RT-qPCR. d Correlation of lncRNA MBNL1-AS1 with a prognosis of NSCLC patients analyzed by Kaplan-Meier curve; *p < 0.05 vs. the adjacent normal tissues, tissues without lymph node metastasis, or BEAS-2B cells. Measurement data were depicted as mean ± standard deviation; data in Fig. 2a was analyzed using a paired t test. Comparisons between two groups were analyzed using the unpaired t test, and comparisons among multiple groups were analyzed using one-way ANOVA with Tukey post hoc test used. The experiment was repeated three times. RT-qPCR, reverse transcription quantitative polymerase chain reaction; ANOVA, analysis of variance

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