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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: microRNA-301b-3p downregulation underlies a novel inhibitory role of long non-coding RNA MBNL1-AS1 in non-small cell lung cancer

Fig. 8

Overexpressed lncRNA MBNL1-AS1 or downregulated miR-301b-3p suppresses xenograft tumor formation in nude mice. a Xenograft tumor formation in nude mice. b Tumor volume of nude mice. c Tumor weight of nude mice. d TGFBR2 protein level determined using western blot analysis. NC group: mice treated with NC. miR-301b-3p-inhibitor group: mice treated with miR-301b-3p inhibition. miR-301b-3p-mimic group: mice treated with miR-301b-3p overexpression. miR-NC + oe-lncRNA MBNL1-AS1 group: mice treated with lncRNA MBNL1-AS1 overexpression and miR-NC. miR-301b-3p-mimic + oe-lncRNA MBNL1-AS1 group: mice treated with lncRNA MBNL1-AS1 overexpression and miR-301b-3p overexpression; *p < 0.05 vs. nude mice treated with NC. Measurement data were depicted as mean ± standard deviation. Comparisons among multiple groups were analyzed using one-way ANOVA with Tukey post hoc test used. The experiment was repeated three times

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