Skip to main content

Advertisement

Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Treatment of knee osteoarthritis with intra-articular injection of autologous adipose-derived mesenchymal progenitor cells: a prospective, randomized, double-blind, active-controlled, phase IIb clinical trial

Fig. 4

Changes of articular cartilage volume by MRI during 12 months after intra-articular injection of Re-Join® and HA. a, b Representative MRI images of the knee joint before and after treatment with Re-Join®. Sagittal views at the height of the patella-femoral condyles before and after 12 months of treatment. The arrows indicate the zones in which treatment generated a mild change in terms of cartilage thickness. c Changes of left knee cartilage volume by MRI in the Re-Join@ and HA groups at baseline and 6 months and 12 months after injection. d Change of right knee cartilage volume by MRI in the Re-Join@ and HA groups at baseline and 6 months and 12 months after injection. e Changes of left knee cartilage volume by MRI of different anatomy location in 6 months after injection. f Changes of right knee cartilage volume by MRI of different anatomy location in 6 months after injection. g Changes of left knee cartilage volume by MRI of different anatomy location in 12 months after injection. h Changes of right knee cartilage volume by MRI of different anatomy location in 12 months after injection. Data was shown in mean and standard deviation. Statistics were determined by Wilcoxon signed rank test. Baseline was shown as 0d, changes of knee cartilage volume were shown as Δ6mw-0d and Δ12m-0d. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page