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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Examining the fundamental biology of a novel population of directly reprogrammed human neural precursor cells

Fig. 2

BMC to drNPC reprogramming. In vitro cultures of bone marrow cells (BMCs) during reprogramming to drNPCs. At early time-points (days 1–3 in vitro), BMC-specific markers CD44, Stro1, and CD90 are expressed and no NPC-specific markers Nestin, Pax6, or Sox2 are observed. By the mid time-points (days 6–7 in vitro), downregulation of BMC-specific markers occurs. At late time-points (days 14–16 in vitro), no BMC-specific markers are observed and NPC-specific markers Nestin, Pax6, and Sox2 are highly expressed. Nuclei stained with Hoechst (blue). Scale bar = 100 μm.

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Stem Cell Research & Therapy

ISSN: 1757-6512