Fig. 5

Hypoxic stress reduced the activity of the Akt/mTOR signaling pathway. a Representative Western blots of p-Akt/Ak, p-mTOR/mTOR, p-p70S6 K/p70S6 K, p-S6/S6, and β-actin in BM-MSCs subjected to normal condition and hypoxic injury for 6, 12, and 24 h, respectively. Quantification of the protein expression levels of p-Akt (b), p-mTOR (c), p-p70S6 K/p70S6 K (d), and p-S6/S6 (e) (n = 5, *p < 0.05)